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Transfer of soft capsule products between 2 CMOs: best practices
The transfer of softgel capsule manufacturing between contract manufacturing organizations (CMOs) is a complex process that is often underestimated.
The manufacturing process of softgel capsules
Soft capsules are commercially manufactured applying the rotary-die technology, a technique that traces its roots back to the 19th century with the innovations of the pharmacist Robert P. Scherer. It involves a series of operations which are performed in parallel to each other and are typically highly standardised at each manufacturer: gel mass preparation, filll mass preparation, encapsulation, drying, inspection and (bulk) packaging.